Which medications are likely to cause hypoglycemia in enterally fed patients?

The correct choice indicates that all listed medications have the potential to cause hypoglycemia in patients who are receiving enteral nutrition. Enterally fed patients may have altered glucose metabolism due to a continuous supply of carbohydrates from the enteral formula. This can heighten the risk of hypoglycemia, especially when certain medications, which influence glucose levels, are administered concurrently.

Sulfonamides can lead to hypoglycemia by interacting with insulin and enhancing its effectiveness, particularly if the patient's diet or oral intake is already compromised. Phenylbutazone, a non-steroidal anti-inflammatory drug (NSAID), can also impact the metabolism of glucose, contributing to lower blood sugar levels.

Propranolol, a non-selective beta-blocker, can blunt the body's typical counter-regulatory response to hypoglycemia, leading patients to experience lower blood glucose without the warning signs they might normally have. Additionally, some barbiturates can enhance insulin secretion or increase sensitivity to insulin, further increasing the risk of hypoglycemia in susceptible individuals.

This awareness of medication interactions with enteral nutrition is critical for healthcare providers working with older adults, as they are often on multiple medications and may have age-related changes in pharmacokinetics and dynamics that intens