Which herbal-drug interaction related to Warfarin causes an increased risk of bleeding?

Ginkgo Biloba is known for its potential to increase the risk of bleeding when taken in conjunction with Warfarin. This herbal supplement has blood-thinning properties and can inhibit platelet aggregation, which may enhance the anticoagulant effects of Warfarin and thereby lead to a higher risk of bleeding complications. This interaction is significant for individuals who are on Warfarin therapy, as it may complicate their management and increase the likelihood of adverse events.

St. John's Wort, while it does interact with Warfarin, typically leads to a decrease in the effectiveness of the anticoagulant by inducing certain liver enzymes that metabolize Warfarin, rather than increasing the risk of bleeding directly. Reiki is a form of alternative therapy that is not classified as a herb and does not have documented interactions with Warfarin.

Thus, Ginkgo Biloba stands out as the correct response, given its well-documented association with an increased risk of bleeding due to its pharmacological action on platelets. Understanding these interactions is critical for safe and effective management of patients on anticoagulant therapy, particularly in older adults who may be using multiple medications and supplements.