Which drug(s) interact with Ascorbic Acid?

Ascorbic acid, commonly known as vitamin C, can interact with several medications, and recognizing these interactions is crucial for gerontological nutrition and the management of elderly patients.

Ascorbic acid can affect the metabolism of estrogen, potentially enhancing its effects, which may cause increased side effects in individuals taking hormone replacement therapy or contraceptives. Understanding this interaction is particularly important for older adults who may be on a regimen that includes estrogen.

In relation to haloperidol, ascorbic acid has been shown to affect the central nervous system by altering neurotransmitter levels. Since haloperidol is an antipsychotic that works by inhibiting dopamine receptors, any alteration in vitamin C levels could possibly influence the drug's effectiveness or the patient's response to treatment.

When it comes to warfarin, a blood thinner frequently prescribed to prevent blood clots, ascorbic acid can influence its anticoagulant activity. High doses of vitamin C may lead to a reduction in warfarin's effectiveness or alter coagulation parameters, leading to an increased risk of clotting or bleeding.

Given these potential interactions, it is important for practitioners in gerontological nutrition to consider the comprehensive implications of concurrent use of ascorbic acid with estrogen, haloperidol,