Which drug is recognized for its interaction with Vitamin D affecting calcium absorption?

Phenytoin is the drug recognized for its interaction with Vitamin D, which affects calcium absorption. This anticonvulsant medication can induce the metabolism of Vitamin D, leading to lower levels of this vital nutrient in the body. Consequently, this can impair calcium absorption from the intestines.

In individuals on phenytoin therapy, it's crucial to monitor vitamin D levels and calcium status, as impaired calcium absorption may contribute to conditions like osteomalacia or osteoporosis, particularly in older adults who might already be at risk for vitamin deficiency.

While digitalis and hydralazine are medications that have various effects on the cardiovascular system, they are not specifically known to interfere with Vitamin D metabolism or calcium absorption in the way that phenytoin does. Therefore, the recognition of phenytoin is particularly significant for understanding its impact on gerontological nutrition, especially concerning calcium-related health.