Which drug can reverse drug-induced peripheral neuropathy when taken with Pyridoxine?

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Pyridoxine, or vitamin B6, is essential for nerve health, and it plays a significant role in the metabolism of neurotransmitters. Certain medications, like isoniazid, are known to induce peripheral neuropathy as a side effect, primarily because they can interfere with the metabolism of vitamin B6 in the body. Co-administration of Pyridoxine with these drugs can help mitigate the peripheral neuropathy by replenishing vitamin B6 levels.

Isoniazid, specifically, is well-documented for causing peripheral neuropathy, and the supplementation with Pyridoxine can effectively reverse these neurological deficits.

Hydralazine and penicillamine are also known to have peripheral neuropathy as a potential adverse effect, and similarly, they can be managed by Pyridoxine supplementation. Given that Pyridoxine can address neuropathic symptoms related to all three of these medications, the option stating that all of the drugs listed can have their drug-induced peripheral neuropathy reversed with pyridoxine is therefore accurate.

Thus, the correct conclusion is that Pyridoxine aids in reversing drug-induced peripheral neuropathy from hydralazine, isoniazid, and penicillamine, making the collective choice

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