What is the only FDA-approved anabolic agent for involuntary weight loss?

Oxandrolone is recognized as the only FDA-approved anabolic agent specifically indicated to address involuntary weight loss, often seen in conditions such as chronic illness or aging. This synthetic derivative of testosterone promotes lean body mass and has been effectively used in clinical settings to facilitate weight gain in patients who have experienced significant weight loss due to medical reasons.

In addition to its role in promoting weight gain, oxandrolone's anabolic properties help enhance muscle recovery and increase strength, making it particularly beneficial for individuals facing severe weight loss. Its approval by the FDA underscores its specific therapeutic application in managing involuntary weight loss, distinguishing it from other options that may have different indications or uses but do not focus primarily on addressing involuntary weight loss.

The other options are associated with bone health and muscle strength improvements but do not hold the same designation for treating involuntary weight loss as oxandrolone does. For instance, teriparatide is primarily used for osteoporosis treatment, romosozumab is indicated for osteoporosis as well, and abaloparatide also serves a similar purpose in treating osteoporosis but lacks the specific application for involuntary weight loss.