What is the effect of aging on the hormone testosterone?

Aging has a significant impact on testosterone levels in both men and women, although the effects are often more pronounced in men. As individuals age, particularly after the age of 30, there is a gradual decline in testosterone production due to changes in the testes and the hypothalamic-pituitary-gonadal axis. This decline can lead to a decrease in testosterone activity, which can manifest as reduced libido, decreased muscle mass, fatigue, and mood changes.

This decline is a normal part of the aging process and is influenced by various factors including health status, chronic illnesses, and lifestyle factors such as diet and exercise. The reduced activity of testosterone in older adults highlights the importance of monitoring hormone levels and understanding how aging affects hormonal balance.

In contrast, increased resistance, increased circulating levels, and reduced sensitivity do not accurately reflect the typical physiological changes related to testosterone as someone ages. Instead, the decline in testosterone activity is a key characteristic of the aging process. Understanding this change can be vital for health care professionals in developing appropriate interventions for older adults experiencing symptoms related to low testosterone levels.